Computational Simulations of Thrombolytic Therapy in Acute Ischaemic Stroke

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منابع مشابه

Thrombolytic therapy for acute ischaemic stroke: is the hype justified?

1. Lau AY, Soo YO, Graham CA, et al. An expedited stroke triage pathway: the key to shortening the door-to-needle time in delivery of thrombolysis. Hong Kong Med J 2010;16:455-62. 2. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 1995;333:1581-7. 3. Kumana CR. Déja Vu. JAMA Southeast Asia...

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Thrombolytic therapy of acute stroke.

Case 1. A 65-year-old right-handed man with no history of heart disease presented to the emergency department with right-sided weakness and an inability to speak. His wife last saw him well 1 hour before his arrival. His ECG showed atrial fibrillation with a ventricular response of 100 bpm; his blood pressure was 175/ 88 mm Hg. He was alert, but he did not produce or comprehend speech. He did n...

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Thrombolytic service of acute ischaemic stroke in Hong Kong.

Since 2004, we have had a 9-to-5 combined intravenous and intra-arterial thrombolytic therapy service in Tuen Mun Hospital. Our efficacy and safety data (presented in local meetings) were comparable to overseas experience. About 50% of our eligible patients were encountered outside office hours, but less than 10% (international standard) received thrombolysis, as cited by Tang1 from unpublished...

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Safety and feasibility of intravenous thrombolytic therapy in Iranian patients with acute ischemic stroke

  Background: Thrombolytic therapy is the only approved treatment for acute cerebral ischemia. The hemorrhagic transformation is the greatest complication of this treatment, which may occur after recanalization of occluded artery. The aim of this study was to determine factors associated with clinical improvement and worsening in patients with acute ischemic stroke treated with intravenous th...

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In-hospital outcomes with thrombolytic therapy in patients with renal dysfunction presenting with acute ischaemic stroke.

BACKGROUND Thrombolytic therapy is an effective treatment modality for acute ischaemic stroke within 3 hours of symptom onset. Its safety and efficacy have not been studied in patients with chronic kidney disease (CKD), who are known to have abnormalities in coagulation and platelet function. METHODS We studied all patients who consecutively received intravenous thrombolytic therapy for acute...

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ژورنال

عنوان ژورنال: Scientific Reports

سال: 2018

ISSN: 2045-2322

DOI: 10.1038/s41598-018-34082-7